Why does sodium retention cause hypertension

For both types, the site of action is in the collecting tubule. The role of spironolactone in resistant hypertension [ 62 ] was discussed earlier. Addition of spironolactone to therapy with other diuretics should always be considered in patients with drug-resistant hypertension providing that there is no hyperkalemia. Serum potassium must be monitored regularly during drug therapy. If adverse effects such as gynecomastia or breast tenderness develop, eplerenone should be substituted as it lacks progesterogenic and antiandrogenic effects.

Hood et al. Remarkably, when used at high-dose, the drugs were equally effective in reducing the blood pressure. Khawaja and C. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Article of the Year Award: Outstanding research contributions of , as selected by our Chief Editors. Read the winning articles.

Journal overview. Special Issues. Khawaja 1 and C. Academic Editor: Vasilios Papademetriou. Received 29 Nov Revised 30 Dec Accepted 13 Jan Published 14 Mar Table 1. References G. Genovese, D.

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Schimmer Bernard and L. Brunton, J. Lazo, and K. Parker, Eds. View at: Google Scholar B. Walker and C. View at: Google Scholar C. Wilcox, X. High blood pressure is an important risk factor for a range of conditions. These include strokes, vascular dementia, diabetes, kidney disease, heart disease and mobility problems. People who already have these conditions may find a reduced salt diet beneficial in the long run.

A high salt diet disrupts the natural sodium balance in the body. This causes fluid retention which increases the pressure exerted by the blood against blood vessel walls high blood pressure. For every one gram of salt we cut from our average daily intake, there would be approximately 6, fewer deaths from strokes and heart attacks each year in the UK.

Working with your doctor to ensure that salt intake is not raising your blood pressure and impacting your heart and kidneys can have a dramatic impact on your health and longevity.

For some people, high salt intake can cause high blood pressure — and create a vicious cycle of heart and kidney damage. Are you at risk? Learn more about vaccine availability. Advertising Policy. You have successfully subscribed to our newsletter. When you think about blood pressure, your kidneys may not come to mind. Related Articles. Trending Topics. What Parents Need to Know.

How Salt Can Impact Your Blood Pressure, Heart and Kidneys For some people, high salt intake can cause high blood pressure — and create a vicious cycle of heart and kidney damage. Share this article via email with one or more people using the form below.